What are the molecular and genetic mechanisms controlling host-microbe interactions? We develop and apply machine learning methods to integrate microbiome and host genomic data to characterize associations between host genes and microbial taxa, and understand how these associations change in health and disease. We aim to answer the following questions:ฤก. Co-Leaders: Ajay Prakash, MD, PhD and Subree Subramanian, PhD. Price New from Used from Hardcover, Decem'Please retry' 81.00 76.79 65.10 Hardcover81.00 1 Used from65.10 3 New from76. The overarching goal is to drive advances in understanding the biology and epidemiology of GI cancers, leading to clinically meaningful improvement in patients with these cancers, both in Minnesota and beyond. We utilize high-throughput genomics technologies and employ computational, statistical, network-theory, data mining, and population genetic analytical approaches, with the goal of understanding how we interact with our microbial communities, how host-microbe interactions affect human disease, and how the symbiosis between us and our microbiome evolved. by Subree Subramanian(Editor), Xianda Zhao(Editor) See all formats and editions Sorry, there was a problem loading this page. 4 Other ACCR Faculty Liz Pluhar and Vicki Wilke (CVM, Surgery) Subree Subramanian (SOM - Surgery) Aaron Sarver (MCC) David Largaespada (MCDBG) Khalil Ahmed. University of Minnesota, Minneapolis, MN, USA e-mail: subree. We study host genomic factors that control and interact with the microbiome. and Subbaya Subramanian Abstract The remarkable success of immunotherapy. In turn, microbes can affect the host by regulating gene expression interacting epithelial cells. Although the human microbiome is influenced by environmental factors, microbial composition is also shaped by host genes and genetic variation. The 1669676326 NPI number is assigned to the healthcare provider SAKTHIRAJ SUBRAMANIAN MD, practice location. Recent advances in high throughput sequencing technologies have unveiled great variability in the microbiome, and shifts in the composition of microbial communities have been associated with multiple health conditions, such as diabetes, inflammatory bowel disease, obesity, and cancer. This webpage represents 1669676326 NPI record. The microbial cells that colonize the human body outnumber host cells by an order of magnitude. Eryaman NEUROSCIENCE Emily Semaya Advisor: Cheryl Olman PHARMACOLOGY Duha Alshareef Advisor: Subree Subramanian Jingyu Cheng Advisor: Colin Campbell.
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